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Oncogene 18 : 173–180 Hatai T, Matsuzawa A, Inoshita S, Mochida Y, Kuroda T, Sakamaki K, Kuida K, Yonehara S, Ichijo H and Takeda K (2000) Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation

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However, we have suggested that persistent, low-level iron accumulation and gradual GSH loss can coexist for extended periods [18] suggesting the possibility of a sustained sub-lethal state