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Epigenetic & Redox Regulation Research Researchers use 5-Amino-1MQ to investigate how NNMT influences epigenetic signaling, oxidative stress responses, and cellular aging pathways

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A multicenter trial in Alzheimer’s disease found no benefit on cognitive or functional outcomes while shifting some biomarkers, a smaller trial in healthy older adults reported improved memory and hippocampal connectivity, and the overall assessment is that it is unlikely to help most healthy adults and that the evidence is not conclusive