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One PTP1B inhibitor, trodusquemine, has been shown to suppress appetite, reduce body weight, and improve plasma insulin and leptin levels in a murine model of diet-induced obesity [52]

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10.1016/j.semcdb.2012.03.017 [DOI] [PMC free article] [PubMed] [Google Scholar] Zhang G., Yao Q., Long C., Yi P., Song J., Wu L., et al